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The Opportunity
Advanced Proteome Therapeutics’ linkage technologies
address improvement of protein therapeutics, a field of enormous
and growing significance. Important factors in this field include:
- The expiration of patents on a number of protein
drugs with annual sales in the billion dollar class creates
major opportunities to improve patient compliance and comfort
by modifying these protein drugs. Modified proteins will
benefit from full patent protection.
- Discovery and development of protein therapeutics continues
to be an area of robust activity.! The FDA has approved over
165 biopharmaceuticals. Hundreds more are in development
and many will require optimization before they can reach
the marketplace.
- APT has an improved
approach to developing carrier-based drug delivery. Annual
sales for protein drugs in this class already exceed several
billion dollars. The field is expanding rapidly. This dynamic
emphasizes the favorable precedents of both regulatory and
market acceptance for such an approach.
- Therapeutic
proteins have the highest rate of sales growth of any type
of drug over the past decade and this trend is expected to
continue in light of current activity. - (IMS Health Global). The
total global market for protein drugs was $47.4 billion in
2006. The market is expected to reach $55.7 billion by the
end of 2011.
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