NOT FOR DISTRIBUTION TO U.S. NEWSWIRE SERVICES OR FOR DISSEMINATION IN THE UNITED STATES

Burnaby, British Columbia / March 25, 2021 – Advanced Proteome Therapeutics Corporation (“APC” or the “Company”) (TSXV: APC) (FSE: 0E8) is pleased to announce that, further to its news release of March 11, 2021 and subject to the approval of the TSX Venture Exchange, it has closed the first tranche of its non-brokered private placement (the “Private Placement”) raising gross proceeds of $633,655.00 by the issuance of 3,091,000 units at a price of $0.205 per unit.

Each unit consists of one common share and one transferable common share purchase warrant of the Company, with each warrant exercisable for a period of 12 months from the date of closing at a price of $0.27 per share.

The Company paid finder’s fees of up to 8% cash and 10% finders’ warrants to Haywood Securities Inc., Leede Jones Gable Inc., IA Capital Markets, Canaccord Genuity Corp., and 10075919 MB LTD. on a portion of the offering. All securities issued in connection with the Private Placement are subject to a 4-month hold period in Canada.

The gross proceeds of the Private Placement will be used for funding of the Company’s subsidiary for research and development activities related to the Company’s site-selective linker technology for the development of antibody-drug conjugates and for general working capital.

The Company confirms that there is no material fact or material change about the Company that has not already been generally disclosed.

ABOUT THE COMPANY:

Advanced Proteome Therapeutics Corporation, through its subsidiary, Advanced Proteome Therapeutics Inc., is developing a proprietary technology to directly target cancerous tumors and avoid destroying normal cells. This type of agent is capable of greater potency, higher specificity, and lower toxicity than other therapies that can also attack healthy cells. Advanced Proteome is working to streamline the process by which these agents are prepared, which to date, has been extremely cumbersome, limiting their potential. www.advancedproteome.com

FOR FURTHER INFORMATION PLEASE CONTACT:

Advanced Proteome Therapeutics Corporation
Paul Woodward
President and CEO
Tel: 604.690.3797
http://www.advancedproteome.com

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

The securities referred to in this news release have not been, nor will they be, registered under the United States Securities Act of 1933, as amended, and may not be offered or sold within the United States or to, or for the account or benefit of, U.S. persons absent U.S. registration or an applicable exemption from the U.S. registration requirements.

This news release does not constitute an offer for sale of securities for sale, nor a solicitation for offers to buy any securities. Any public offering of securities in the United States must be made by means of a prospectus containing detailed information about the company and management, as well as financial statements.